Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors

Shepherd JD, Rumbaugh G, Wu J, Chowdhury S, Plath N, Kuhl D, Huganir RL, Worley PF (2006). Neuron, 52(3):475-84.

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Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

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Triple-transgenic model of Alzheimer’s disease with plaques and tangles: intracellular Abeta and synaptic dysfunction